The ZNF366 Polyclonal Antibody (PAC031276) is a valuable tool for researchers studying ZNF366, a zinc finger protein involved in gene regulation and cellular processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in applications such as Western blotting.ZNF366, also known as a transcription factor, plays a crucial role in regulating gene expression and controlling cellular functions. Research into ZNF366 is essential for understanding its role in various biological processes, such as development, differentiation, and disease progression.
By targeting ZNF366 with this polyclonal antibody, researchers can detect and analyze its expression in different cell types, making it an excellent tool for studies in genetics and molecular biology.Overall, the ZNF366 Polyclonal Antibody (PAC031276) offers a reliable and specific tool for researchers investigating the function and regulation of ZNF366 in various biological contexts. Its high reactivity with human samples makes it an ideal choice for studies focused on understanding the role of ZNF366 in health and disease.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO31276 at dilution of 1:100.
Immunofluorescent analysis of A549 cells using PACO31276 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO31276 at dilution of 1:100.
Background:
Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.
Synonyms:
Zinc finger protein 366 (Dendritic cell-specific transcript protein) (DC-SCRIPT), ZNF366
UniProt Protein Function:
ZNF366: Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.Protein type: Nuclear receptor co-regulator; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 5q13.2|5q13.2Cellular Component: nucleusMolecular Function: estrogen receptor binding; protein binding; transcription corepressor activityBiological Process: negative regulation of estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; response to estrogen stimulus
