The ZNF365 Polyclonal Antibody (PAC020957) is a vital tool for researchers studying zinc finger protein 365 (ZNF365), a key player in DNA repair and genomic stability. This rabbit-raised antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ZNF365 protein, researchers can effectively detect and analyze its expression in a variety of cell types, making it an essential component of studies in genetics, cancer biology, and DNA damage response mechanisms.ZNF365 plays a crucial role in maintaining the integrity of the genome by facilitating DNA repair processes and promoting genomic stability.
Dysregulation of ZNF365 has been implicated in various diseases, including cancer, developmental disorders, and neurodegenerative conditions. By studying the function and regulation of ZNF365, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new targets for therapeutic interventions. Grab the ZNF365 Polyclonal Antibody today and take your research to the next level.
Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane: Human liver cancer tissue, Primary antibody: PACO20957(ZNF365 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20957(ZNF365 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid, nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified.
Synonyms:
zinc finger protein 365
UniProt Protein Function:
ZNF365: several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified. [provided by RefSeq, May 2010]Protein type: Unknown functionChromosomal Location of Human Ortholog: 10q21.2Molecular Function: protein bindingDisease: Nephrolithiasis, Uric Acid, Susceptibility To
UniProt Protein Details:
NCBI Summary:
This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified. [provided by RefSeq, May 2010]