ZNF346 Rabbit Polyclonal Antibody (CAB7507)
- SKU:
- CAB7507
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ZNF346 Rabbit Polyclonal Antibody |
SKU: | CAB7507 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-294 of human ZNF346 (NP_036411.1). |
Sequence: | MEYP APAT VQAA DGGA AGPY SSSE LLEG QEPD GVRF DRER ARRL WEAV SGAQ PVGR EEVE HMIQ KNQC LFTN TQCK VCCA LLIS ESQK LAHY QSKK HANK VKRY LAIH GMET LKGE TKKL DSDQ KSSR SKDK NQCC PICN MTFS SPVV AQSH YLGK THAK NLKL KQQS TKVE ALHQ NREM IDPD KFCS LCHA TFND PVMA QQHY VGKK HRKQ ETKL KLMA RYGR LADP AVTD FPAG KGYP CKTC KIVL NSIE QYQA HVSG FKHK NQSP KTVA SSLG QIPM QRQP IQKD STTL ED |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | JAZ; Zfp346; ZNF346 |
Positive Sample: | A-549,MCF7,THP-1,HeLa,Mouse testis,Mouse heart,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 33kDa |
Observed MW: | 33-38kDa |
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23567 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |