The ZNF346 Polyclonal Antibody (CAB7507) is a valuable tool for researchers studying ZNF346, a zinc finger protein involved in gene regulation and RNA processing. This antibody, generated in rabbits, shows high specificity and sensitivity towards human samples, making it ideal for applications such as Western blot and immunofluorescence.ZNF346 is known to play a role in various cellular processes, including transcriptional regulation and mRNA splicing, making it a key player in gene expression control. The ZNF346 Polyclonal Antibody enables researchers to detect and analyze ZNF346 protein levels in different cell types, allowing for insights into its function and potential implications in diseases such as cancer and neurological disorders.
By targeting ZNF346, researchers can gain a better understanding of its role in cellular function and how dysregulation may contribute to disease development. This antibody provides a reliable tool for investigating ZNF346 and its involvement in various biological processes, making it a valuable asset for studies in molecular biology and disease mechanisms.
Product Name:
ZNF346 Rabbit Polyclonal Antibody
SKU:
CAB7507
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-294 of human ZNF346 (NP_036411.1).
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ZNF346 antibody (CAB7507) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
