The ZNF282 Polyclonal Antibody (PACO60873) is a valuable tool for researchers studying ZNF282, a zinc finger protein involved in gene regulation and transcriptional control. This antibody is raised in rabbits and has been validated for use in various applications, including Western blot and immunohistochemistry. ZNF282 is known to play a crucial role in developmental processes and has been implicated in diseases such as cancer and neurological disorders. By targeting ZNF282 with this polyclonal antibody, researchers can better understand its function and potential implications in various biological pathways.
With its high reactivity towards human samples, this antibody is a reliable tool for exploring the role of ZNF282 in disease development and progression. Its specificity and sensitivity make it ideal for use in a wide range of research studies focused on gene regulation and transcriptional dynamics.
Antibody Name:
ZNF282 Antibody (PACO60873)
Antibody SKU:
PACO60873
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Zinc finger protein 282 protein (240-384AA)
IHC image of PACO60873 diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression.
Synonyms:
Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1), ZNF282, HUB1
UniProt Protein Function:
Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression.
