The ZNF260 Polyclonal Antibody (PACO31240) is a research tool designed for studying the ZNF260 protein, a transcription factor involved in gene regulation. Raised in rabbits, this antibody is highly specific for targeting human ZNF260 and has been validated for use in Western blot applications. By binding to the ZNF260 protein, researchers can accurately detect and analyze its expression in various cell types, making it a valuable asset for studies in molecular biology and cancer research.
ZNF260, also known as zinc finger protein 260, plays a crucial role in controlling gene expression and cell function. Its involvement in regulating key cellular processes makes it an interesting target for investigating diseases such as cancer, developmental disorders, and neurological conditions. Delving into the functions of ZNF260 is essential for unraveling its impact on cellular pathways and potentially identifying new therapeutic strategies for related disorders.
Antibody Name:
ZNF260 Antibody (PACO31240)
Antibody SKU:
PACO31240
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Zinc finger protein 260 protein (1-200AA)
Immunohistochemistry of paraffin-embedded human skin tissue using PACO31240 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO31240 at dilution of 1:100.
Background:
Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator.
Synonyms:
Zinc finger protein 260 (Zfp-260), ZNF260, ZFP260
UniProt Protein Function:
ZNF260: Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: DNA-binding; Transcription regulation; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.12Cellular Component: cytoplasm; nucleoplasmMolecular Function: protein binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent
