The ZNF189 Polyclonal Antibody (CAB16446) is a valuable tool for researchers studying the ZNF189 protein, a transcription factor involved in gene regulation and cellular processes. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in various applications, including Western blotting.ZNF189 is known to regulate gene expression and play a role in cellular functions such as proliferation, differentiation, and apoptosis.
Studies have shown its involvement in diseases like cancer and neurological disorders, making it a promising target for further research. The ZNF189 Polyclonal Antibody enables detection and analysis of ZNF189 protein in different cell types, providing valuable insights for researchers in the fields of genetics, oncology, and neurobiology. Unlock the potential of ZNF189 with this reliable and specific antibody.
Product Name:
ZNF189 Rabbit Polyclonal Antibody
SKU:
CAB16446
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human ZNF189 (NP_001265160.1).
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.
Purification Method:
Affinity purification
Gene ID:
7743
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using ZNF189 Rabbit pAb (CAB16446) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
