The ZMYM3 Polyclonal Antibody (CAB12990) is a valuable tool for researchers studying the ZMYM3 protein, which has been implicated in various cellular processes including transcriptional regulation and chromatin organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ZMYM3 protein, researchers can easily detect and analyze its expression in different cell types, making it an ideal choice for studies in molecular biology and cancer research.
ZMYM3, also known as ZNF261, is a zinc finger protein that plays a key role in gene regulation and chromatin remodeling. Its involvement in these processes suggests its potential significance in various diseases, including cancer and developmental disorders. By investigating the function of ZMYM3 with the help of this antibody, researchers can gain insights into its role in cellular pathways and potentially identify new therapeutic targets for disease treatment.
Product Name:
ZMYM3 Rabbit Polyclonal Antibody
SKU:
CAB12990
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1).
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9203
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using ZMYM3 Rabbit pAb (CAB12990) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
