ZMPSTE24 Rabbit Polyclonal Antibody (CAB18593)
- SKU:
- CAB18593
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ZMPSTE24 Rabbit Polyclonal Antibody |
SKU: | CAB18593 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ZMPSTE24 (NP_005848.2). |
Sequence: | AWLF TLVV SLVL VTIY ADYI APLF DKFT PLPE GKLK EEIE VMAK SIDF PLTK VYVV EGSK RSSH SNAY FYGF FKNK RIVL FDTL LEEY SVLN KDIQ EDSG M |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HGPS; PRO1; FACE1; RSDM1; STE24; FACE-1; Ste24p; ZMPSTE24 |
Positive Sample: | SKOV3 |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein, Nucleus inner membrane. |
Calculated MW: | 55kDa |
Observed MW: | 54kDa |
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
Purification Method: | Affinity purification |
Gene ID: | 10269 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |