The ZMIZ2 Polyclonal Antibody (CAB17301) is a valuable tool for research involving the ZMIZ2 protein, which is known to play a critical role in gene transcription and cell signaling pathways. This antibody, raised in rabbits, has a high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ZMIZ2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.ZMIZ2, also known as zinc finger MIZ domain-containing protein 2, is implicated in regulating the expression of genes involved in cell growth and differentiation.
Its functions in gene transcription and signaling make it a key player in various biological processes, including development and disease progression. Research on ZMIZ2 could provide valuable insights into mechanisms underlying cancer, neurological disorders, and other diseases, offering potential targets for therapeutic interventions.Overall, the ZMIZ2 Polyclonal Antibody is a versatile research tool for investigating the functions and regulatory roles of the ZMIZ2 protein in different cellular contexts. Its high specificity and reliability in experimental applications make it a valuable asset for scientists exploring the complex biology of gene expression and signaling pathways.
Product Name:
ZMIZ2 Rabbit Polyclonal Antibody
SKU:
CAB17301
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human ZMIZ2 (NP_001287888).
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).
Purification Method:
Affinity purification
Gene ID:
83637
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZMIZ2 Rabbit pAb (CAB17301) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.