The ZMAT5 Polyclonal Antibody (PACO40698) is a valuable tool for research involving the zinc finger matrin-type 5 (ZMAT5) protein, which plays a critical role in gene regulation and DNA repair processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.ZMAT5 is involved in the regulation of gene expression, particularly in response to cellular stress and DNA damage. Its function in DNA repair pathways makes it a key player in maintaining genomic integrity and cell survival.
Research on ZMAT5 is essential for understanding its role in diseases such as cancer, where dysregulation of DNA repair mechanisms can lead to genomic instability and tumorigenesis.By using the ZMAT5 Polyclonal Antibody, researchers can detect and analyze ZMAT5 protein levels in various cell types, providing insights into its function and potential therapeutic implications. This antibody is a valuable tool for studies in molecular biology, cancer research, and other fields where gene regulation and DNA repair processes are of interest.
Western blot. All lanes: ZMAT5 antibody at 5µg/ml + Colo320 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 20 kDa. Observed band size: 20 kDa.
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO40698 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO40698 at dilution of 1:100.
Synonyms:
Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein) (U11/U12-20K), ZMAT5
UniProt Protein Function:
ZMAT5: Component of the U11/U12 snRNPs that are part of the U12- type spliceosome. Not found in the major spliceosome. Chromosomal Location of Human Ortholog: 22cen-q12.3Cellular Component: nucleoplasm; U12-dependent spliceosomeBiological Process: nuclear mRNA splicing, via spliceosome; RNA splicing
