The ZKSCAN5 Polyclonal Antibody (PAC058608) is a valuable tool for researchers studying the ZKSCAN5 protein, which is involved in gene regulation and chromosomal organization. This antibody, produced in rabbits, exhibits high specificity for human samples and is recommended for Western blot applications. By binding to the ZKSCAN5 protein, this antibody enables the detection and analysis of ZKSCAN5 expression in various cell types, making it ideal for use in studies related to genetics, epigenetics, and chromatin remodeling.ZKSCAN5 is a transcription factor that plays a crucial role in the regulation of gene expression and the maintenance of genomic stability.
Its involvement in chromatin organization and DNA replication processes underscores its importance in cellular function and development. Research on ZKSCAN5 is particularly relevant to understanding mechanisms of gene regulation, cellular differentiation, and disease processes such as cancer.Overall, the ZKSCAN5 Polyclonal Antibody is a valuable tool for researchers investigating the functions and regulatory mechanisms of the ZKSCAN5 protein in various biological contexts. Its high specificity and sensitivity make it a reliable asset for studies in genetics, cell biology, and disease research.
Antibody Name:
ZKSCAN5 Antibody (PACO58608)
Antibody SKU:
PACO58608
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Zinc finger protein with KRAB and SCAN domains 5 protein (490-643AA)
IHC image of PACO58608 diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of PACO58608 diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
May be involved in transcriptional regulation.
Synonyms:
Zinc finger protein with KRAB and SCAN domains 5 (Zinc finger protein 95 homolog) (Zfp-95), ZKSCAN5, KIAA1015 ZFP95
UniProt Protein Function:
ZFP95: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: Transcription factor; C2H2-type zinc finger protein; DNA-bindingChromosomal Location of Human Ortholog: 7q22Molecular Function: protein binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation. A similar protein in mouse is differentially expressed in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
