The ZKSCAN5 Polyclonal Antibody (PAC021990) is a vital tool for researchers studying the ZKSCAN5 protein, which plays a key role in gene regulation and transcriptional repression. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications. By targeting the ZKSCAN5 protein, this antibody enables precise detection and analysis in various cell types, facilitating research endeavors in molecular biology and cancer studies.ZKSCAN5, a transcriptional repressor, exerts its influence on gene expression by binding to specific DNA sequences and modulating transcriptional activity.
Its regulatory functions have been implicated in various biological processes, making it a promising target for investigating gene regulation mechanisms and associated pathologies, such as cancer development and progression. By delving into the intricacies of ZKSCAN5 activity, researchers can gain insights that may pave the way for novel therapeutic strategies targeting gene regulatory networks.
Antibody Name:
ZKSCAN5 Antibody (PACO21990)
Antibody SKU:
PACO21990
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ZNF95.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Immunofluorescence analysis of A549 cells, using ZNF95 antibody.
Synonyms:
Zinc finger protein with KRAB and SCAN domains 5; Zinc finger protein 95 homolog; Zfp-95; ZKSCAN5; KIAA1015
UniProt Protein Function:
ZFP95: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: Transcription factor; C2H2-type zinc finger protein; DNA-bindingChromosomal Location of Human Ortholog: 7q22Molecular Function: protein binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation. A similar protein in mouse is differentially expressed in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
