The ZKSCAN4 Polyclonal Antibody (PAC038398) is a vital tool for researchers studying ZKSCAN4, a transcription factor known for its role in stem cell differentiation and pluripotency. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, and has been validated for use in Western blot applications.ZKSCAN4 is a key regulator of gene expression in stem cells, influencing their ability to differentiate into various cell types. Its involvement in pluripotency maintenance and differentiation pathways makes it a crucial target for research in regenerative medicine and developmental biology. By detecting and analyzing ZKSCAN4 protein expression in different cell types, this antibody aids in understanding the molecular mechanisms underlying stem cell fate determination.
Furthermore, ZKSCAN4 has been implicated in cancer progression and metastasis, highlighting its potential as a therapeutic target in oncology research. Investigating the function of ZKSCAN4 is essential for unraveling its role in tumorigenesis and identifying possible therapeutic interventions for cancer treatment. The ZKSCAN4 Polyclonal Antibody is a valuable tool for researchers aiming to elucidate the biological functions and regulatory mechanisms of ZKSCAN4 in various cellular processes and disease contexts.
Antibody Name:
ZKSCAN4 Antibody (PACO38398)
Antibody SKU:
PACO38398
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Zinc finger protein with KRAB and SCAN domains 4 protein (264-545AA)
May be involved in the transcriptional activation of MDM2 and EP300 genes.
Synonyms:
Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427), ZKSCAN4, ZNF307 ZNF427
UniProt Protein Function:
ZKSCAN4: May be involved in the transcriptional activation of MDM2 and EP300 genes. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger protein; DNA-bindingChromosomal Location of Human Ortholog: 6p21Cellular Component: nucleusMolecular Function: protein binding; sequence-specific DNA binding; transcription factor activityBiological Process: lysosome organization and biogenesis; negative regulation of autophagy
