The ZKSCAN4 Polyclonal Antibody (PACO02013) is a valuable tool for researchers studying ZKSCAN4, a transcriptional repressor that plays a crucial role in gene regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for ZKSCAN4 in human samples, making it an ideal choice for Western blot applications. By targeting the ZKSCAN4 protein, this antibody enables precise detection and analysis in a variety of cell types, facilitating investigations in the fields of molecular biology and cancer research.ZKSCAN4, also known as zinc finger and SCAN domain-containing protein 4, is involved in modulating gene expression and has been implicated in various cellular processes, such as cell proliferation and differentiation.
Its unique functions make it a promising target for studies on development, differentiation, and disease progression. By understanding the regulatory mechanisms governed by ZKSCAN4, researchers can gain insights into potential therapeutic strategies for conditions like cancer, genetic disorders, and developmental abnormalities.
Antibody Name:
ZKSCAN4 Antibody
Antibody SKU:
PACO02013
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human ZKSCAN4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ZKSCAN4; ZNF307; ZNF427; Zinc finger protein with KRAB and SCAN domains 4; P373c6.1; Zinc finger protein 307; Zinc finger protein 427
UniProt Protein Function:
ZKSCAN4: May be involved in the transcriptional activation of MDM2 and EP300 genes. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger protein; DNA-bindingChromosomal Location of Human Ortholog: 6p21Cellular Component: nucleusMolecular Function: protein binding; sequence-specific DNA binding; transcription factor activityBiological Process: lysosome organization and biogenesis; negative regulation of autophagy
