The ZIP12 Polyclonal Antibody (CAB16006) is a versatile tool for studying the ZIP12 protein, a zinc transporter that plays a crucial role in cellular zinc homeostasis and metabolism. This antibody is raised in rabbits and has been validated for use in Western blot applications, making it a reliable choice for researchers studying zinc transport and metabolism.ZIP12 is a member of the ZIP family of zinc transporters, which are responsible for maintaining intracellular zinc levels and regulating cellular processes such as growth, development, and immune function.
As such, research on ZIP12 can provide insights into the role of zinc in various physiological processes and its implications for health and disease.The ZIP12 Polyclonal Antibody binds specifically to the ZIP12 protein, allowing for easy detection and analysis in a variety of cell types and experimental conditions. With its high reactivity with human samples, this antibody is well-suited for studies in biochemistry, cell biology, and nutrition, providing valuable data on the function and regulation of ZIP12 in different biological contexts.
Product Name:
Zip12 Rabbit Polyclonal Antibody
SKU:
CAB16006
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC39A12 (NP_001138667.1).
extracellular vesicle, perinuclear region of cytoplasm, plasma membrane
Calculated MW:
77kDa
Observed MW:
77kDa
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).
Purification Method:
Affinity purification
Gene ID:
221074
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Zip12 Rabbit pAb (CAB16006) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
