The ZIP1 Polyclonal Antibody (PAC063587) is a valuable tool for researchers studying the ZIP1 protein, which plays a key role in zinc transport and homeostasis within cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ZIP1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in the fields of molecular biology and metal ion transport research.ZIP1 is a member of the ZIP family of zinc transporters, responsible for regulating the intracellular levels of zinc and facilitating its transport across cell membranes. Proper zinc homeostasis is essential for numerous biological processes, including gene expression, enzymatic reactions, and DNA repair.
Dysregulation of ZIP1 has been implicated in various diseases, such as cancer, neurodegenerative disorders, and diabetes, highlighting its significance as a potential therapeutic target.By utilizing the ZIP1 Polyclonal Antibody in experimental studies, researchers can gain valuable insights into the mechanisms underlying zinc transport and its impact on cellular function. This antibody offers a reliable tool for investigating the role of ZIP1 in health and disease, paving the way for the development of targeted therapies aimed at restoring zinc homeostasis and addressing related disorders.
Antibody Name:
ZIP1 Antibody (PACO63587)
Antibody SKU:
PACO63587
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Saccharomyces cerevisiae
Immunogen:
Recombinant Saccharomyces cerevisiae Synaptonemal complex protein ZIP1 protein (1-227AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: ZIP1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 29 kDa. Observed band size: 43 kDa.
Background:
Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.
Synonyms:
Synaptonemal complex protein ZIP1, ZIP1
UniProt Protein Function:
Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.Miscellaneous: Present with 391 molecules/cell in log phase SD medium.
