The Zinc Transporter 6 Polyclonal Antibody (CAB11644) is a valuable tool for researchers studying zinc transporter 6 (ZnT6), a key player in cellular zinc homeostasis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding specifically to the ZnT6 protein, this antibody allows for the detection and analysis of ZnT6 in various cell types, making it an essential tool for studies in cell biology and metal ion transport.ZnT6 is a vital transporter protein responsible for regulating intracellular zinc levels, which play a crucial role in a wide range of cellular processes, including gene transcription, enzyme activity, and signal transduction.
Dysregulation of zinc homeostasis has been linked to various diseases, making ZnT6 an attractive target for research in areas such as neurodegenerative disorders, diabetes, and cancer. Understanding the function of ZnT6 can provide valuable insights into the mechanisms underlying these diseases and may lead to the development of novel therapeutic strategies aimed at targeting zinc transport pathways.
Product Name:
SLC30A6 Rabbit Polyclonal Antibody
SKU:
CAB11644
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 252-461 of human SLC30A6 (NP_060434.2).
This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's disease brain plaques.
Purification Method:
Affinity purification
Gene ID:
55676
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC30A6 Rabbit pAb (CAB11644) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
