ZIC2 Rabbit Polyclonal Antibody (CAB15736)
- SKU:
- CAB15736
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | ZIC2 Rabbit Polyclonal Antibody |
SKU: | CAB15736 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ZIC2 (NP_009060.2). |
Sequence: | MLLD AGPQ FPAI GVGS FARH HHHS AAAA AAAA AEMQ DREL SLAA AQNG FVDS AAAH MGAF KLNP GAHE LSPG QSSA FTSQ GPGA YPGS AAAA AAAA ALGP HAAH VGSY SGPP FNST RDFL FRSR GFGD SAPG GGQH GLFG PGAG GLHH AHSD AQGH LLFP GLPE QHGP HGSQ NVLN GQMR LGLP GEVF GRSE QYRQ VASP RTDP YSAA QLHN QYGP MNMN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HPE5; ZIC2 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 55kDa |
Observed MW: | 50kDa |
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Purification Method: | Affinity purification |
Gene ID: | 7546 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |