ZHX1 Antibody (PACO13307)
- SKU:
- PACO13307
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ZHX1 Antibody (PACO13307)
The ZHX1 Polyclonal Antibody (PAC013307) is a crucial tool for researchers studying the ZHX1 protein, which is involved in gene regulation and plays a role in various cellular processes. This antibody is raised in rabbits and specifically reacts with human samples, making it suitable for a wide range of research applications. Validated for use in Western blot, immunohistochemistry, and immunofluorescence, this antibody allows for the detection and analysis of ZHX1 protein expression in different cell types.
ZHX1, a transcriptional repressor, is known to regulate the expression of genes involved in cell proliferation, differentiation, and development. Its intricate role in gene regulation makes it a key target for investigation in fields such as cancer research and developmental biology. By understanding the function of ZHX1, researchers can gain insights into the underlying mechanisms of various diseases and potentially identify novel therapeutic targets.
| Antibody Name: | ZHX1 Antibody (PACO13307) |
| Antibody SKU: | PACO13307 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human ZHX1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | zinc fingers and homeoboxes 1; |
| UniProt Protein Function: | ZHX1: Acts as a transcriptional repressor. Increases DNMT3B- mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co- repressor proteins. Belongs to the ZHX family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 8q24.13 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; DNA binding; protein heterodimerization activity; metal ion binding; transcription corepressor activity; transcription factor activity Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; cell differentiation; negative regulation of transcription, DNA-dependent |
| UniProt Code: | Q9UKY1 |
| NCBI GenInfo Identifier: | 44888551 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9UKY1.1 |
| Molecular Weight: | |
| NCBI Full Name: | Zinc fingers and homeoboxes protein 1 |
| UniProt Protein Name: | Zinc fingers and homeoboxes protein 1 |
| Protein Family: | Zinc fingers and homeoboxes protein |
| UniProt Gene Name: | ZHX1Â Â |
| UniProt Entry Name: | ZHX1_HUMAN |
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