The ZGRF1 Polyclonal Antibody (PAC037574) is a valuable tool for researchers studying ZGRF1, a protein involved in DNA repair and maintenance processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ZGRF1 in human samples, making it suitable for use in Western blot applications. By binding to the ZGRF1 protein, this antibody enables precise detection and analysis, aiding in the exploration of DNA repair mechanisms in various cell types.ZGRF1, also known as Zinc finger GRF-type containing 1, plays a crucial role in maintaining genomic stability and preventing DNA damage accumulation.
Dysregulation of ZGRF1 has been linked to genetic disorders and cancer development, highlighting its significance in cellular health. Research on ZGRF1 opens opportunities for understanding and potentially targeting DNA repair pathways in disease conditions, paving the way for innovative therapeutic strategies in cancer treatment and genetic disorders.
Immunofluorescent analysis of U251 cells using PACO37574 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1), ZGRF1, C4orf21
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The encoded protein contains GRF zinc finger (zf-GRF) and transmembrane domains. GRF zinc fingers are found in a number of DNA-binding proteins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2017]
