The ZGPAT Polyclonal Antibody (CAB16583) is a valuable tool for researchers studying the ZGPAT protein, a key player in DNA damage response and genome stability. This antibody, produced in rabbits, is highly specific and reactive towards human samples, making it suitable for various applications including Western blot analysis.ZGPAT, also known as Zinc finger CCCH-type antiviral protein 1, is involved in RNA metabolism and has been implicated in the regulation of antiviral responses. Its role in maintaining genomic integrity and responding to cellular stress make it a promising target for research in the fields of DNA repair, cancer biology, and virology.
By utilizing the ZGPAT Polyclonal Antibody, researchers can accurately detect and analyze ZGPAT protein levels in different cell types, providing valuable insights into its function and potential implications in disease. This antibody is a valuable tool for advancing our understanding of ZGPAT and its role in cellular processes, paving the way for innovative research and therapeutic development.
Antibody Name:
Anti-ZGPAT Antibody
Antibody SKU:
CAB16583
Antibody Size:
20uL, 50uL, 100uL
Application:
WB
Reactivity:
Rat
Host Species:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 212-511 of human ZGPAT (NP_852150.2).
Application:
WB
Recommended Dilution:
WB 1:500 - 1:2000
Reactivity:
Rat
Positive Samples:
Rat lung
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 212-511 of human ZGPAT (NP_852150.2).
Purification Method:
Affinity purification
Storage Buffer:
Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ZGPAT, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP
Background:
UniProt Protein Function:
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
zinc finger CCCH-type with G patch domain-containing protein isoform d
NCBI Synonym Full Names:
zinc finger CCCH-type and G-patch domain containing
NCBI Official Symbol:
ZGPATÂ Â
NCBI Official Synonym Symbols:
ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847Â Â
NCBI Protein Information:
zinc finger CCCH-type with G patch domain-containing protein
UniProt Protein Name:
Zinc finger CCCH-type with G patch domain-containing protein
UniProt Synonym Protein Names:
G patch domain-containing protein 6; Zinc finger CCCH domain-containing protein 9; Zinc finger and G patch domain-containing protein
UniProt Gene Name:
ZGPATÂ Â
Western blot analysis of extracts of rat lung, using ZGPAT antibody (CAB16583) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s.
