The ZFYVE9 Polyclonal Antibody (CAB9041) is a valuable tool for researchers studying the ZFYVE9 protein, also known as Protrudin. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ZFYVE9 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in cell biology and neuroscience.ZFYVE9 plays a crucial role in intracellular membrane trafficking and organelle dynamics, particularly in the regulation of endosomal compartments and neurite outgrowth.
Its involvement in these processes makes it a target of interest in research on neurodegenerative diseases, such as Alzheimer's and Parkinson's, as well as cellular mechanisms related to vesicle transport and neuronal development.By using the ZFYVE9 Polyclonal Antibody, researchers can delve deeper into the functions and interactions of the ZFYVE9 protein, shedding light on its role in cellular processes and potential implications in disease pathology. This antibody offers a reliable tool for exploring the intricacies of ZFYVE9 biology and expanding our understanding of its impact on neurological function and pathology.
Product Name:
ZFYVE9 Rabbit Polyclonal Antibody
SKU:
CAB9041
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZFYVE9 (NP_004790.2).
This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9372
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ZFYVE9 antibody (CAB9041) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
