The ZFYVE27 Polyclonal Antibody (CAB15942) is a valuable tool for researchers studying ZFYVE27, a protein involved in endosomal trafficking and autophagy processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ZFYVE27 protein, this antibody allows for the detection and analysis of ZFYVE27 expression in various cell types, making it an ideal choice for studies in cell biology and molecular biology.ZFYVE27, also known as zinc finger FYVE-type containing 27, plays a crucial role in the regulation of intracellular trafficking and autophagosome formation.
Dysregulation of ZFYVE27 has been associated with various diseases, including neurodegenerative disorders and cancer. Therefore, understanding the function and regulation of ZFYVE27 is essential for developing targeted therapies and interventions for these conditions.Overall, the ZFYVE27 Polyclonal Antibody (CAB15942) offers researchers a reliable tool for investigating the role of ZFYVE27 in cellular processes and disease pathogenesis, providing valuable insights for the development of novel therapeutic strategies.
Product Name:
ZFYVE27 Rabbit Polyclonal Antibody
SKU:
CAB15942
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 217-411 of human ZFYVE27 (NP_653189.3).
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
Purification Method:
Affinity purification
Gene ID:
118813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat eye, using ZFYVE27 Rabbit pAb (CAB15942) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
