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ZFP36L2 Antibody (PACO13301)

SKU:
PACO13301
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459

Description

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ZFP36L2 Antibody (PACO13301)

The ZFP36L2 Polyclonal Antibody (PAC013301) is a crucial tool for researchers studying the ZFP36L2 protein, which is involved in post-transcriptional regulation of gene expression. This antibody, produced in rabbits, exhibits high specificity and sensitivity to human samples, making it an ideal choice for Western blot applications. By binding to the ZFP36L2 protein, this antibody enables the detection and analysis of ZFP36L2 in a variety of cell types, facilitating research in molecular biology and gene regulation.ZFP36L2, also known as TTP family member 2, plays a key role in mRNA degradation and turnover, influencing gene expression patterns and cellular responses.

Its involvement in post-transcriptional control makes it a target of interest for studies on cell signaling, RNA metabolism, and developmental biology. The ZFP36L2 Polyclonal Antibody provides researchers with a valuable tool for unraveling the complex mechanisms underlying gene regulation and protein synthesis, offering insights into various physiological and pathological processes.

Antibody Name:ZFP36L2 Antibody (PACO13301)
Antibody SKU:PACO13301
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human ZFP36L2
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:zinc finger protein 36, C3H type-like 2;ZFP36L2;BRF2;ERF-2;ERF2;RNF162C;TIS11D ;
UniProt Protein Function:ZFP36L2: Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.
UniProt Protein Details:

Protein type:Transcription factor

Chromosomal Location of Human Ortholog: 2p22.3-p21

Cellular Component: cytoplasm; nucleus

Molecular Function:AU-rich element binding; transcription factor activity

Biological Process: cell proliferation; hemopoiesis; mRNA catabolic process; somatic stem cell division; somatic stem cell maintenance

NCBI Summary:This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq, Jul 2008]
UniProt Code:P47974
NCBI GenInfo Identifier:146291085
NCBI Gene ID:678
NCBI Accession:P47974.3
UniProt Secondary Accession:P47974,Q53TB4, Q9BSJ3,
UniProt Related Accession:P47974
Molecular Weight:51,063 Da
NCBI Full Name:Zinc finger protein 36, C3H1 type-like 2
NCBI Synonym Full Names:ZFP36 ring finger protein like 2
NCBI Official Symbol:ZFP36L2  
NCBI Official Synonym Symbols:BRF2; ERF2; ERF-2; TIS11D; RNF162C  
NCBI Protein Information:zinc finger protein 36, C3H1 type-like 2
UniProt Protein Name:Zinc finger protein 36, C3H1 type-like 2
UniProt Synonym Protein Names:Butyrate response factor 2; EGF-response factor 2; ERF-2; Protein TIS11D
Protein Family:mRNA decay activator protein
UniProt Gene Name:ZFP36L2  
UniProt Entry Name:TISD_HUMAN

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