The ZFP30 Polyclonal Antibody (PAC020948) is a valuable tool for researchers studying the ZFP30 protein, a zinc finger transcription factor involved in gene regulation and cell differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in a variety of experimental applications, including Western blot analysis.ZFP30 is known to play a key role in the regulation of gene expression, particularly in processes related to cell growth and development. This antibody specifically targets the ZFP30 protein, allowing for precise detection and analysis in different cell types and experimental conditions.
Its versatility makes it an ideal choice for studies in molecular biology, developmental biology, and stem cell research.The ZFP30 Polyclonal Antibody is a valuable tool for researchers looking to elucidate the function and mechanisms of action of the ZFP30 protein in various biological processes. By understanding the role of ZFP30, researchers can gain insights into complex regulatory networks and pathways that may be relevant in the context of development, disease, and therapeutic interventions.
Antibody Name:
ZFP30 Antibody (PACO20948)
Antibody SKU:
PACO20948
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human ZFP30
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20948(ZFP30 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20948(ZFP30 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
ZFP30 (zinc finger protein 30 homolog) is a 519 amino acid, protein that localizes to the nucleus and is composed of thirteen C2H2-type zinc fingers and one KRAB domain. ZFP30 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fc receptors (FcRs).
Synonyms:
ZFP30 zinc finger protein
UniProt Protein Function:
ZFP30: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.12Molecular Function: transcription factor activityBiological Process: regulation of transcription, DNA-dependent
