The ZFP30 Polyclonal Antibody (PAC020947) is a valuable tool for researchers studying Zinc Finger Protein 30 (ZFP30), a transcription factor involved in gene regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.ZFP30 is known for its role in controlling gene expression and has been implicated in a variety of cellular processes, including development, differentiation, and immune response.
By targeting the ZFP30 protein, this antibody enables the detection and analysis of ZFP30 in different cell types, making it an excellent choice for studies in molecular biology, developmental biology, and immunology.Given the importance of ZFP30 in regulating gene expression and cellular function, further research into its mechanisms of action could provide valuable insights into various biological processes and potentially lead to the development of novel therapeutics for a range of diseases and conditions.
Antibody Name:
ZFP30 Antibody (PACO20947)
Antibody SKU:
PACO20947
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human ZFP30
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20947(ZFP30 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
ZFP30 (zinc finger protein 30 homolog) is a 519 amino acid, protein that localizes to the nucleus and is composed of thirteen C2H2-type zinc fingers and one KRAB domain. ZFP30 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fc receptors (FcRs).
Synonyms:
ZFP30 zinc finger protein
UniProt Protein Function:
ZFP30: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.12Molecular Function: transcription factor activityBiological Process: regulation of transcription, DNA-dependent
