The ZEB1 Polyclonal Antibody (CAB5600) is a valuable tool for researchers studying ZEB1, a transcription factor known for its role in regulating epithelial-to-mesenchymal transition (EMT) in cancer and development. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By targeting the ZEB1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in oncology and developmental biology.ZEB1 is a key player in the process of EMT, which is crucial for tumor invasion and metastasis in cancer progression.
Additionally, ZEB1 is involved in a variety of developmental processes, making it a versatile target for research in various biological contexts. Understanding the function of ZEB1 is essential for elucidating its role in cancer biology and development, and this antibody provides researchers with a reliable tool for investigating ZEB1-mediated mechanisms in these fields.Overall, the ZEB1 Polyclonal Antibody (CAB5600) offers researchers a high-quality reagent for studying the molecular mechanisms regulated by ZEB1 in cancer and development, ultimately advancing our knowledge of these complex biological processes.
Product Name:
ZEB1 Rabbit Polyclonal Antibody
SKU:
CAB5600
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ZEB1 (NP_110378.3).
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
6935
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Human mammary cancer using ZEB1 Rabbit pAb (CAB5600) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
