The ZDHHC8 Polyclonal Antibody (CAB17348) is a high-quality research tool designed for the study of ZDHHC8, a member of the DHHC family of palmitoyl acyltransferases. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ZDHHC8 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for researchers in the fields of cell biology and neuroscience.ZDHHC8 plays a crucial role in the process of protein palmitoylation, which involves the attachment of fatty acids to proteins and is important for membrane localization and protein-protein interactions.
Dysregulation of palmitoylation has been implicated in various diseases, including cancer, neurological disorders, and metabolic conditions. By studying the function and regulation of ZDHHC8, researchers can gain insights into the mechanisms underlying these pathologies and potentially identify novel therapeutic targets.Overall, the ZDHHC8 Polyclonal Antibody (CAB17348) offers researchers a reliable tool for investigating the role of ZDHHC8 in cellular processes and disease pathogenesis, ultimately contributing to advancements in biomedical research and drug development.
Product Name:
ZDHHC8 Rabbit Polyclonal Antibody
SKU:
CAB17348
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ZDHHC8 (NP_037505.1).
This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.
Purification Method:
Affinity purification
Gene ID:
29801
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZDHHC8 Rabbit pAb (CAB17348) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
