The ZDHHC7 Polyclonal Antibody (CAB17981) is a valuable tool for researchers studying ZDHHC7, an enzyme involved in protein palmitoylation and membrane trafficking. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ZDHHC7 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it ideal for investigations in cell biology and neuroscience.ZDHHC7 is a key player in post-translational modification processes, specifically the addition of lipid groups to proteins, which can regulate protein localization and function.
Dysregulation of protein palmitoylation has been linked to neurodegenerative diseases and cancer, highlighting the importance of understanding the role of ZDHHC7 in these contexts. By studying the activity of ZDHHC7, researchers can gain insights into the mechanisms underlying disease pathology and potentially identify new targets for therapeutic intervention.
Product Name:
ZDHHC7 Rabbit Polyclonal Antibody
SKU:
CAB17981
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 210 to the C-terminus of human ZDHHC7 (NP_060210.2).
Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; polarized epithelial cell differentiation; and regulation of signal transduction. Located in Golgi apparatus and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
55625
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZDHHC7 Rabbit pAb (CAB17981) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
