The ZDHHC5 Polyclonal Antibody (CAB18114) is a vital tool for researchers studying the ZDHHC5 protein, a member of the DHHC palmitoyltransferase family involved in protein palmitoylation and membrane targeting. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ZDHHC5 plays a crucial role in the regulation of various cellular processes, including cell signaling, protein trafficking, and synaptic plasticity. Dysregulation of ZDHHC5 has been linked to neurological disorders, making it a promising target for further investigation in neuroscience research.
By binding specifically to the ZDHHC5 protein, this antibody enables precise detection and analysis in different cell types, providing valuable insights into the functions and mechanisms of ZDHHC5-mediated palmitoylation processes. Its versatility and reliability make it an essential tool for studies in cell biology, neurobiology, and molecular biology, facilitating a better understanding of ZDHHC5's role in health and disease.
Product Name:
ZDHHC5 Rabbit Polyclonal Antibody
SKU:
CAB18114
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 130-230 of human ZDHHC5 (NP_056272.2).
Enables palmitoyltransferase activity. Involved in positive regulation of pattern recognition receptor signaling pathway and positive regulation of protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in phagocytic vesicle and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
25921
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using ZDHHC5 Rabbit pAb (CAB18114) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
