The ZDHHC2 Polyclonal Antibody (CAB17979) is an essential tool for research involving ZDHHC2, a palmitoyl transferase enzyme that plays a crucial role in protein palmitoylation, a key post-translational modification involved in various cellular processes. This antibody, derived from rabbit immunoglobulins, demonstrates high specificity for human samples and has been validated for use in Western blot applications. By binding to the ZDHHC2 protein, this antibody enables the detection and analysis of ZDHHC2 expression levels in different cell types, making it a valuable tool for studies in cell biology, metabolism, and neurobiology.ZDHHC2 is known to be involved in the palmitoylation of a variety of proteins, including receptors and ion channels, impacting their localization, stability, and function within the cell.
Dysregulation of palmitoylation processes has been linked to various diseases, including neurological disorders, cancer, and metabolic conditions. By studying ZDHHC2 and its role in protein palmitoylation, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially uncover new therapeutic targets for intervention. The ZDHHC2 Polyclonal Antibody is a valuable resource for advancing our understanding of ZDHHC2 function and its implications in health and disease.
Product Name:
ZDHHC2 Rabbit Polyclonal Antibody
SKU:
CAB17979
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 270-367 of human ZDHHC2 (NP_057437.1).
Enables protein homodimerization activity and protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of protein catabolic process; and regulation of protein localization to plasma membrane. Located in Golgi apparatus and endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
51201
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZDHHC2 Rabbit pAb (CAB17979) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
