The ZDHHC1 Polyclonal Antibody (PACO48022) is a valuable tool for researchers studying ZDHHC1, an enzyme involved in palmitoylation, a post-translational modification important for protein localization and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting ZDHHC1 in human samples, making it a reliable choice for experiments involving Western blot analysis.ZDHHC1, also known as palmitoyltransferase ZDHHC1, plays a crucial role in palmitoylation, a lipid modification that regulates protein trafficking, stability, and function. Dysregulation of ZDHHC1 has been implicated in various diseases, including cancer, neurological disorders, and immune-related conditions.
By studying the function and expression of ZDHHC1, researchers can gain insights into the molecular mechanisms underlying these diseases and potential therapeutic targets.The ZDHHC1 Polyclonal Antibody is a valuable tool for investigating the role of ZDHHC1 in cellular processes, making it a valuable asset for studies in cell biology, biochemistry, and drug discovery. Its high specificity and sensitivity ensure reliable and reproducible results, enabling researchers to advance our understanding of palmitoylation and its implications in health and disease.
Western Blot. Positive WB detected in: Mouse spleen tissue. All lanes: C16orf1 antibody at 2.6µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 55 kDa. Observed band size: 55 kDa..
Immunofluorescent analysis of A549 cells using PACO48022 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO48022 at dilution of 1:100.
Background:
endoplasmic reticulum, extracellular exosome, DNA binding, palmitoyltransferase activity, protein palmitoylation
Synonyms:
Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 1) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377), ZDHHC1, C16orf1 ZNF377
UniProt Protein Function:
ZDHHC1: Belongs to the DHHC palmitoyltransferase family.Protein type: Membrane protein, multi-pass; Transferase; EC 2.3.1.225; Membrane protein, integralChromosomal Location of Human Ortholog: 16q22.1Cellular Component: endoplasmic reticulum; integral to membraneMolecular Function: DNA binding; palmitoyltransferase activity; protein-cysteine S-palmitoleyltransferase activity; zinc ion bindingBiological Process: protein palmitoylation
