The ZCCHC4 Polyclonal Antibody (CAB10144) is a valuable tool for researchers investigating the ZCCHC4 protein, which is involved in RNA binding and processing. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the ZCCHC4 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and RNA-related research.ZCCHC4, a zinc finger protein, plays a crucial role in RNA metabolism by regulating RNA splicing and processing. Its function in RNA modification makes it a key player in gene expression regulation and post-transcriptional modifications.
Understanding the role of ZCCHC4 is essential for unraveling the complex mechanisms of RNA biology and exploring its implications in various diseases, such as cancer, neurodegenerative disorders, and developmental abnormalities.Researchers aiming to investigate the molecular functions of ZCCHC4 and its impact on RNA processing will benefit from the specificity and reliability of the ZCCHC4 Polyclonal Antibody (CAB10144). With its validated performance in Western blot assays, this antibody offers a valuable tool for studying the intricate processes of RNA biology and the potential therapeutic applications in related fields.
Product Name:
ZCCHC4 Rabbit Polyclonal Antibody
SKU:
CAB10144
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-220 of human ZCCHC4 (NP_079212.2).
Enables S-adenosyl-L-methionine binding activity; rRNA (adenine-N6-)-methyltransferase activity; and zinc ion binding activity. Involved in positive regulation of translation and rRNA methylation. Located in cytoplasm and nucleolus.
Purification Method:
Affinity purification
Gene ID:
29063
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse kidney, using ZCCHC4 antibody (CAB10144) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.