The ZCCHC13 Polyclonal Antibody (PAC038642) is a valuable tool for researchers studying ZCCHC13, a zinc finger protein involved in RNA metabolism and gene regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the ZCCHC13 protein, this antibody enables the detection and analysis of ZCCHC13 in various cell types, making it an essential tool for research in molecular biology and RNA biology.ZCCHC13 is known to play a critical role in RNA processing, specifically in the regulation of mRNA stability and translation.
Dysregulation of ZCCHC13 has been implicated in various diseases, including cancer and neurological disorders. Therefore, understanding the mechanisms and functions of ZCCHC13 is crucial for developing targeted therapies and treatments for these conditions.Overall, the ZCCHC13 Polyclonal Antibody (PAC038642) is a valuable resource for researchers interested in unraveling the molecular mechanisms of RNA metabolism and gene regulation, with potential implications for disease treatment and therapeutic development.
Antibody Name:
ZCCHC13 Antibody (PACO38642)
Antibody SKU:
PACO38642
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Zinc finger CCHC domain-containing protein 13 protein (1-166AA)
Immunohistochemistry of paraffin-embedded human testis tissue using PACO38642 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO38642 at dilution of 1:100.
Synonyms:
Zinc finger CCHC domain-containing protein 13, ZCCHC13
UniProt Protein Function:
ZCCHC13: Chromosomal Location of Human Ortholog: Xq13.2Molecular Function: nucleic acid binding; zinc ion binding
UniProt Protein Details:
NCBI Summary:
This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 3. However, the CDS of this intronless gene remains relatively intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. The encoded protein contains six CCHC-type zinc fingers, and is thus thought to function as a transcription factor. [provided by RefSeq, May 2010]
