The ZC3H12A Polyclonal Antibody (CAB12667) is a valuable tool for researchers studying ZC3H12A, a zinc finger protein known for its role in regulating inflammatory responses. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ZC3H12A protein, researchers can detect and analyze its expression in various cell types, making it an ideal choice for studies in immunology and inflammatory disorders.
ZC3H12A, also referred to as Regnase-1, is a key player in controlling the degradation of inflammatory mRNAs, thereby modulating the immune response. Its function in regulating inflammation and immune homeostasis makes it a promising target for research in autoimmune diseases, inflammatory conditions, and cancer. Understanding the mechanisms by which ZC3H12A influences immune responses is vital for developing new therapeutic strategies to treat these complex diseases.
Product Name:
ZC3H12A Rabbit Polyclonal Antibody
SKU:
CAB12667
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ZC3H12A (NP_079355.2).
ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.
Purification Method:
Affinity purification
Gene ID:
80149
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZC3H12A Rabbit pAb (CAB12667) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
