The ZBTB8OS Antibody (PAC037838) is a polyclonal antibody designed for research involving ZBTB8OS, a protein involved in cellular processes and gene regulation. The antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various research applications. It is validated for use in Western blotting, immunofluorescence, and immunoprecipitation assays, allowing for easy detection and analysis of ZBTB8OS in different cell types.ZBTB8OS is known to play a role in gene transcription and regulation, making it a key player in cellular function and development. Its significance in gene expression makes it a valuable target for research into various biological processes, including cell proliferation, differentiation, and apoptosis.
Understanding the function and regulation of ZBTB8OS is crucial for advancing our knowledge of cellular biology and potentially developing new therapies for related diseases.Overall, the ZBTB8OS Antibody (PAC037838) is a valuable tool for researchers studying ZBTB8OS and its role in cellular processes. Its high specificity and reactivity make it a reliable option for various research applications, providing valuable insights into the function and regulation of this important protein.
Western blot. All lanes: ZBTB8OS antibody at 8µg/ml + HL60 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 20, 16 kDa. Observed band size: 20 kDa.
Immunofluorescent analysis of HepG2 cells using PACO37838 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO37838 at dilution of 1:100.
Background:
Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation.
Synonyms:
Protein archease (Protein ZBTB8OS) (Zinc finger and BTB domain-containing opposite strand protein 8), ZBTB8OS, ARCH
UniProt Protein Function:
ZBTB8OS: Belongs to the archease family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 1p35.1Cellular Component: nucleoplasmMolecular Function: metal ion bindingBiological Process: gene expression; tRNA processing; tRNA splicing
