The Anti-ZBTB7A (FBI-1/LRF) Antibody (CAB19785) is a valuable tool for researchers studying the ZBTB7A protein, which is involved in diverse cellular processes including transcriptional regulation, tumor suppression, and hematopoiesis. This polyclonal antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot and immunohistochemistry applications.ZBTB7A, also known as FBI-1 or LRF, plays a crucial role in gene expression regulation and has been implicated in various diseases such as cancer and hematological malignancies.
Understanding the function and regulation of ZBTB7A is essential for unraveling its role in normal cellular physiology and disease pathogenesis. This antibody enables detection and analysis of ZBTB7A in different cell types, making it an ideal tool for studies in cancer biology, immunology, and drug development.
Product Name:
ZBTB7A/FBI-1/LRF Rabbit Monoclonal Antibody
SKU:
CAB19785
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human ZBTB7A/FBI-1/LRF (O95365).
Enables several functions, including SMAD binding activity; androgen receptor binding activity; and transcription corepressor binding activity. Involved in several processes, including erythrocyte maturation; negative regulation of signal transduction; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. Colocalizes with DNA-dependent protein kinase complex and NuRD complex.
Purification Method:
Affinity purification
Gene ID:
51341
Clone Number:
ARC2320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZBTB7A/FBI-1/LRF Rabbit mAb (CAB19785) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
