The ZBTB17 Polyclonal Antibody (CAB8463) is a crucial tool for researchers studying ZBTB17, a transcription factor involved in various biological processes, including cell differentiation, proliferation, and apoptosis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blotting and immunohistochemistry applications. By binding to the ZBTB17 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an invaluable resource for studies in fields such as cell biology, cancer research, and developmental biology.
ZBTB17, also known as MIZ-1, acts as a transcriptional repressor or activator depending on its interacting partners, and dysregulation of ZBTB17 has been implicated in various diseases, including cancer and developmental disorders. By studying the function and regulation of ZBTB17, researchers can gain insights into its role in disease pathology and potentially identify therapeutic targets for intervention. The ZBTB17 Polyclonal Antibody (CAB8463) is an essential tool for unraveling the complexities of ZBTB17 biology and its impact on human health.
Product Name:
ZBTB17 Rabbit Polyclonal Antibody
SKU:
CAB8463
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-360 of human ZBTB17 (NP_003434.2).
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18.
Purification Method:
Affinity purification
Gene ID:
7709
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZBTB17 Rabbit pAb (CAB8463) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
