The ZBTB16 Polyclonal Antibody (CAB5863) is a valuable tool for researchers studying the ZBTB16 protein, also known as PLZF, which plays a key role in cell differentiation and immune regulation. This antibody is raised in rabbits and has been validated for use in Western blot applications, allowing for the detection and analysis of ZBTB16 in various cell types.ZBTB16 is involved in the regulation of gene expression and plays a crucial role in the development and function of immune cells. Dysregulation of ZBTB16 has been implicated in various diseases, including cancer and autoimmune disorders.
Understanding the function of ZBTB16 is essential for developing targeted therapies for these conditions.By using the ZBTB16 Polyclonal Antibody, researchers can further investigate the role of ZBTB16 in immune regulation and disease pathogenesis, ultimately leading to the development of potential treatments and interventions. This antibody is a valuable tool for studies in immunology, oncology, and other related fields.
Product Name:
PLZF Rabbit Polyclonal Antibody
SKU:
CAB5863
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 199-300 of human PLZF (NP_005997.2).
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
Purification Method:
Affinity purification
Gene ID:
7704
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLZF Rabbit pAb (CAB5863) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
