The ZBP1 Polyclonal Antibody (CAB13899) is an essential tool for researchers studying ZBP1, a protein involved in immune signaling pathways and host defense against viral infections. This antibody, produced in rabbits, has high specificity for ZBP1 and is validated for use in techniques such as Western blotting. By binding specifically to the ZBP1 protein, this antibody allows for precise detection and analysis of ZBP1 expression in a variety of cell types.ZBP1, also known as DAI, is a cytoplasmic sensor that plays a crucial role in detecting viral nucleic acids and initiating innate immune responses.
Its involvement in triggering the antiviral immune signaling cascade makes it a key target for investigating immune responses to viral infections and developing antiviral therapies. Researchers studying viral pathogenesis, host-virus interactions, and immune cell activation will find the ZBP1 Polyclonal Antibody to be an invaluable tool for their research endeavors.
Product Name:
ZBP1 Rabbit Polyclonal Antibody
SKU:
CAB13899
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ZBP1 (NP_110403.2).
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
81030
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse spleen, using ZBP1 Rabbit pAb (CAB13899) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
