The ZAR1 Polyclonal Antibody (PAC022765) is a valuable tool for researchers studying the ZAR1 protein, an essential factor in mammalian early embryogenesis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the ZAR1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in developmental biology and reproductive medicine.
ZAR1 is a key player in the regulation of embryonic genome activation and maternal-to-zygotic transition, critical processes in early embryonic development. Its role in controlling gene expression and embryo viability highlights its importance in understanding fertility, pregnancy, and reproductive disorders. Research on ZAR1 opens up possibilities for advancing assisted reproduction techniques, improving infertility treatments, and unraveling the mysteries of early human development.
Antibody Name:
ZAR1 Antibody (PACO22765)
Antibody SKU:
PACO22765
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human ZAR1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from 293 cells, using ZAR1 antibody.
Background:
Essential for female fertility. May play a role in the oocyte-to-embryo transition By similarity.
ZAR1: Essential for female fertility. May play a role in the oocyte-to-embryo transition. Belongs to the ZAR1 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 4p11
UniProt Protein Details:
NCBI Summary:
This maternal effect gene is oocyte-specific and encodes a protein that is thought to function in the initiation of embryogenesis. A similar protein in mouse is required for female fertility. [provided by RefSeq, Jul 2013]
