ZAP70 Rabbit Monoclonal Antibody (CAB9536)
- SKU:
- CAB9536
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | ZAP70 Rabbit Monoclonal Antibody |
SKU: | CAB9536 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-619 of human ZAP70 (NP_001070.2). |
Sequence: | SDVW SYGV TMWE ALSY GQKP YKKM KGPE VMAF IEQG KRME CPPE CPPE LYAL MSDC WIYK WEDR PDFL TVEQ RMRA CYYS LASK VEGP PGST QKAE AACA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 |
Synonyms: | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70; ZAP70 |
Positive Sample: | Jurkat,MOLT-4,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Peripheral membrane protein. |
Calculated MW: | 70kDa |
Observed MW: | 73kDa |
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7535 |
Clone Number: | ARC51229 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |