ZAK Rabbit Polyclonal Antibody (CAB7371)
- SKU:
- CAB7371
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ZAK Rabbit Polyclonal Antibody |
SKU: | CAB7371 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human ZAK (NP_598407.1). |
Sequence: | MSSL GASF VQIK FDDL QFFE NCGG GSFG SVYR AKWI SQDK EVAV KKLL KIEK EAEI LSVL SHRN IIQF YGVI LEPP NYGI VTEY ASLG SLYD YINS NRSE EMDM DHIM TWAT DVAK GMHY LHME APVK VIHR DLKS RNVV IAAD GVLK ICDF GASR FHNH TTHM SLVG TFPW MAPE VIQS LPVS ETCD TYSY GVVL WEML TREV PFKG LEGL QVAW LVVE KNER LTIP SSCP RSFA ELLH QCWE ADAK KRPS FKQI ISIL ESMS NDTS LPDK CNSF LHNK AEWR CEIE ATLE RLKK LERD LSFK EQEL KERE RRLK MWEQ KLTE QSNT PL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:20 - 1:50 |
Synonyms: | pk; AZK; MLT; MRK; ZAK; CNM6; MLK7; MLTK; SFMMP; mlklak; MLTKbeta; MLTKalpha |
Positive Sample: | MCF7,A-549,HepG2,Mouse lung,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 35kDa/51kDa/91kDa |
Observed MW: | 55kDa/91kDa/100kDa |
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 51776 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |