The YY2 Polyclonal Antibody (CAB16621) is a valuable tool for researchers studying YY2, a transcription factor that plays a crucial role in gene regulation and cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the YY2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.YY2 is a key player in the regulation of gene expression, influencing important cellular functions such as cell growth, differentiation, and apoptosis.
Its involvement in various signaling pathways makes it a promising target for investigations into cancer development and progression. By gaining a deeper understanding of YY2's mechanisms of action, researchers can uncover new insights into the molecular pathways underlying cancer and potentially identify novel therapeutic targets for the treatment of cancer.
Product Name:
YY2 Rabbit Polyclonal Antibody
SKU:
CAB16621
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human YY2 (NP_996806.2).
The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14.
Purification Method:
Affinity purification
Gene ID:
404281
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using YY2 Rabbit pAb (CAB16621) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
