The YY1 Polyclonal Antibody (CAB12928) is a valuable tool for researchers studying the transcription factor Yin Yang 1 (YY1), which plays a crucial role in regulating gene expression and cell proliferation. This antibody, produced by AssayGenie, is raised in rabbits and specifically targets the YY1 protein in human samples. YY1 is known to be involved in a variety of cellular processes, including DNA repair, apoptosis, and development. It is also implicated in diseases such as cancer, where dysregulation of YY1 can contribute to tumor growth and progression.
The YY1 Polyclonal Antibody is validated for use in Western blot applications, allowing for the detection and analysis of YY1 in different cell types.By using the YY1 Polyclonal Antibody, researchers can gain valuable insights into the function of YY1 and its impact on various biological pathways. This antibody is an essential tool for studies in molecular biology, cancer research, and developmental biology, providing a better understanding of YY1's role in health and disease.
Product Name:
YY1 Rabbit Polyclonal Antibody
SKU:
CAB12928
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-160 of human YY1 (NP_003394.1).
Sequence:
HPPM IALQ PLVT DDPT QVHH HQEV ILVQ TREE VVGG DDSD GLRA EDGF EDQI LIPV PAPA GGDD DYIE QTLV TVAA AGKS G
Tested Applications:
WBChIPELISA
Recommended Dilution:
WB,1:500 - 1:1000 ChIP,5μg antibody for 10μg-15μg of Chromatin
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Purification Method:
Affinity purification
Gene ID:
7528
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using YY1 Rabbit pAb (CAB12928) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
