The YWHAG Polyclonal Antibody (CAB3043) is a valuable tool for research involving YWHAG, a protein involved in multiple cellular processes, including signal transduction and cell cycle regulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the YWHAG protein, researchers can detect and analyze its expression in various cell types, making it an ideal choice for studies in cell biology and cancer research.YWHAG, also known as 14-3-3 gamma, is a key player in signal transduction pathways, acting as a molecular scaffold that regulates the activity of its binding partners.
Its involvement in cell cycle progression and apoptosis makes it a promising target for research into diseases such as cancer, where dysregulation of these processes can occur. Understanding the function of YWHAG is essential for gaining insights into its role in cellular physiology and disease pathology, paving the way for potential therapeutic interventions.
Product Name:
14-3-3 gamma Rabbit Polyclonal Antibody
SKU:
CAB3043
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human 14-3-3 gamma (NP_036611.2).
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Purification Method:
Affinity purification
Gene ID:
7532
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using 14-3-3 gamma Rabbit pAb (CAB3043) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
