The YTHDF3 Polyclonal Antibody (CAB8395) is a vital tool for researchers studying YTHDF3, a key player in the regulation of mRNA stability and translation. This antibody, produced in rabbits, shows high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By binding to the YTHDF3 protein, researchers can easily detect and analyze its expression in various cell types, providing valuable insights into RNA biology and potential therapeutic targets.YTHDF3 is a member of the YTH domain-containing family of proteins, which are important for mRNA metabolism and protein synthesis. It specifically recognizes and binds to m6A-modified mRNA, influencing its degradation or translation efficiency.
Research on YTHDF3 has revealed its involvement in various cellular processes, including cell proliferation, differentiation, and stress responses. Understanding the function of YTHDF3 is essential for unraveling the complexities of gene expression regulation and its impact on cellular functions.The YTHDF3 Polyclonal Antibody opens up new possibilities for investigating the role of YTHDF3 in different biological contexts, such as cancer development, stem cell differentiation, and viral infections. With its reliable performance and robust validation, this antibody offers researchers a valuable tool for advancing our understanding of RNA biology and its implications in human health and disease.
Product Name:
YTHDF3 Rabbit Polyclonal Antibody
SKU:
CAB8395
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human YTHDF3 (NP_689971.4).
This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
253943
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using YTHDF3 Rabbit pAb (CAB8395) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
