The YTHDF1 Polyclonal Antibody (CAB18126) is specifically designed for research involving YTHDF1, a key player in mRNA regulation and RNA metabolism. This rabbit-derived antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the YTHDF1 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in molecular biology and gene expression.YTHDF1 is a member of the YTH domain family of proteins and is known to play a crucial role in the regulation of mRNA stability and translation.
Its involvement in processes such as RNA methylation and decay makes it a valuable target for research in fields such as cancer biology and developmental biology. Understanding the function of YTHDF1 can provide insights into mechanisms underlying diseases like cancer and neurological disorders, paving the way for potential therapeutic interventions targeting this protein.
Product Name:
YTHDF1 Rabbit Polyclonal Antibody
SKU:
CAB18126
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-390 of human YTHDF1 (NP_060268.2).
Enables N6-methyladenosine-containing RNA binding activity and ribosome binding activity. Involved in mRNA destabilization; positive regulation of translational initiation; and stress granule assembly. Located in P-body and cytoplasmic stress granule.
Purification Method:
Affinity purification
Gene ID:
54915
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using YTHDF1 antibody (CAB18126) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
