YTHDC2 Rabbit Polyclonal Antibody (CAB15004)
- SKU:
- CAB15004
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | YTHDC2 Rabbit Polyclonal Antibody |
SKU: | CAB15004 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1131-1430 of human YTHDC2 (NP_073739.3). |
Sequence: | HSLF LRRM RAPS KPWS QVDE ATIR AIIA VLST EEQS AGLQ QPSG IGQR PRPM SSEE LPLA SSWR SNNS RKSS ADTE FSDE CTTA ERVL MKSP SPAL HPPQ KYKD RGIL HPKR GTED RSDQ SSLK STDS SSYP SPCA SPSP PSSG KGSK SPSP RPNM PVRY FIMK SSNL RNLE ISQQ KGIW STTP SNER KLNR AFWE SSIV YLVF SVQG SGHF QGFS RMSS EIGR EKSQ DWGS AGLG GVFK VEWI RKES LPFQ FAHH LLNP WNDN KKVQ ISRD GQEL EPLV GEQL LQLW ERLP LGEK NTTD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CAHL; hYTHDC2; YTHDC2 |
Positive Sample: | HeLa,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum, nucleus, perinuclear region of cytoplasm |
Calculated MW: | 160kDa |
Observed MW: | 160kDa |
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
Purification Method: | Affinity purification |
Gene ID: | 64848 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |